منابع مشابه
Design and Evaluation of Liposomal Formulation of Pilocarpine Nitrate
Prolonged release drug delivery system of pilocarpine nitrate was made by optimizing thin layer film hydration method. Egg phosphatidylcholine and cholesterol were used to make multilamellar vesicles. Effects of charges over the vesicles were studied by incorporating dicetylphosphate and stearylamine. Various factors, which may affect the size, shape, encapsulation efficiency and release rate, ...
متن کاملAlbumin Microspheres as an Ocular Delivery System for Pilocarpine Nitrate
Pilocarpine nitrate loaded egg albumin microspheres were prepared by thermal denaturation process in the size range of 1-12 mum. A series of batches were prepared to study factors, which may affect the size and entrapment efficiency of drug in microspheres and optimized the process. Drug loaded microspheres so obtained were evaluated for their size, entrapment efficiency, release rate and biolo...
متن کاملTranstympanic pilocarpine in tinnitus.
In 48 patients who had neurosensory hypoacusia and whose main complaint was tinnitus, a 1% pilocarpine solution or a 2% carbachol Isopto solution was placed in the tympanic cavity by means of a No. 26 pencil-tipped lumbar puncture needle through the front quadrant of the eardrum. Patients were chosen without regard for age, gender, or topographical damage of the acoustic pathway. Evaluation of ...
متن کاملThe effect of pilocarpine on tumor growth.
The administration of pilocarpine has been shown to increase tissue levels of specific proteins in several biological systems, possibly by exerting an effect on protein synthesis. Litarczek has shown that the administration of pilocarpine causes an increased antibody production in rabbits given inoculations of typhus bacillus (6), and recent investigations have indicated that an in creased accu...
متن کاملEffects of Pilocarpine on Ocular Tension Dynamics.
Pilocarpine has been used since 1877 in the treatment of glaucoma because of its effect in lowering intraocular pressure. How ever, it is only since the advent of tonography and anterior chamber perfusion tech niques that the mechanism of this effect has been investigated. It was the purpose of this study to evalu ate further the effects of pilocarpine by means of diurnal tonometric and tono...
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ژورنال
عنوان ژورنال: The Boston Medical and Surgical Journal
سال: 1877
ISSN: 0096-6762,1533-4406
DOI: 10.1056/nejm187708020970507